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糖尿病患者口腔健康问题的证据状况:文献综述

State of Evidence on Oral Health Problems in Diabetic Patients: A Critical Review of the Literature.

作者信息

González-Moles Miguel Ángel, Ramos-García Pablo

机构信息

School of Dentistry, University of Granada, 18010 Granada, Spain.

Instituto de Investigación Biosanitaria ibs.GRANADA, 18012 Granada, Spain.

出版信息

J Clin Med. 2021 Nov 18;10(22):5383. doi: 10.3390/jcm10225383.

DOI:10.3390/jcm10225383
PMID:34830663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8618619/
Abstract

Diabetes mellitus (DM) is a global health problem, having recognized that in the next 20 years the number of diabetic patients in the world will increase to 642 million. DM exerts enormous repercussions on general health diabetic (especially derived from vascular, cardiac, renal, ocular, or neurological affectation). It entails in addition a high number of deaths directly related to the disease, as well as a high health care cost, estimated at $673 billion annually. Oral cavity is found among all the organs and systems affected in the course of DM. Important pathologies are developed with higher prevalence, such as periodontitis (PD), alterations in salivary flow, fungal infections, oral cancer, and oral potentially malignant disorders (OPMD). It has been proven that PD hinders the metabolic control of DM and that the presence of PD increases the possibility for developing diabetes. Despite the relevance of these oral pathologies, the knowledge of primary care physicians and diabetes specialists about the importance of oral health in diabetics, as well as the knowledge of dentists about the importance of DM for oral health of patients is scarce or non-existent. It is accepted that the correct management of diabetic patients requires interdisciplinary teams, including dentists. In this critical review, the existing knowledge and evidence-degree on the preventive, clinical, diagnosis, prognosis, and therapeutic aspects of oral diseases that occur with a significant frequency in the diabetic population are developed in extension.

摘要

糖尿病(DM)是一个全球性的健康问题,据认识到在未来20年世界上糖尿病患者的数量将增加到6.42亿。糖尿病对糖尿病患者的总体健康产生巨大影响(特别是源于血管、心脏、肾脏、眼部或神经方面的影响)。此外,它还导致大量与该疾病直接相关的死亡,以及高昂的医疗保健成本,估计每年达6730亿美元。口腔是糖尿病病程中受影响的所有器官和系统之一。会出现患病率更高的重要病症,如牙周炎(PD)、唾液分泌改变、真菌感染、口腔癌和口腔潜在恶性疾病(OPMD)。已经证明,牙周炎会阻碍糖尿病的代谢控制,并且牙周炎的存在会增加患糖尿病的可能性。尽管这些口腔病症很重要,但初级保健医生和糖尿病专家对糖尿病患者口腔健康重要性的了解,以及牙医对糖尿病对患者口腔健康重要性的了解却很少或不存在。人们公认,糖尿病患者的正确管理需要跨学科团队,包括牙医。在这篇批判性综述中,对糖尿病患者中频繁出现的口腔疾病在预防、临床、诊断、预后和治疗方面的现有知识和证据程度进行了详细阐述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3498/8618619/37474b8ef829/jcm-10-05383-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3498/8618619/37474b8ef829/jcm-10-05383-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3498/8618619/37474b8ef829/jcm-10-05383-g001.jpg

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Cancers (Basel). 2021 Sep 28;13(19):4843. doi: 10.3390/cancers13194843.
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A Scoping Review on Gaps in the Diagnostic Criteria for Proliferative Verrucous Leukoplakia: A Conceptual Proposal and Diagnostic Evidence-Based Criteria.增殖性疣状白斑诊断标准差距的范围综述:概念性建议和基于诊断证据的标准
Cancers (Basel). 2021 Jul 21;13(15):3669. doi: 10.3390/cancers13153669.
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Oral Health Messiers: Diabetes Mellitus Relevance.
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BMC Oral Health. 2025 Apr 11;25(1):546. doi: 10.1186/s12903-025-05815-8.
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