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分子靶向治疗药物相关性间质性肺疾病的高分辨率 CT 表现

Drug-induced interstitial lung disease in molecular targeted therapies: high-resolution CT findings.

机构信息

Department of Diagnostic Radiology, Saitama International Medical Center, Saitama Medical University, Hidaka, Saitama, 350-1298, Japan.

出版信息

Int J Clin Oncol. 2012 Dec;17(6):542-50. doi: 10.1007/s10147-012-0489-2. Epub 2012 Nov 10.

Abstract

Drug-induced lung injury (DLI) comprises a wide variety of pathologies, each with a unique imaging pattern, so there are no characteristic imaging findings to establish diagnosis. When DLI is suspected, evaluation must exclude progression of underlying disease, infection, and mimicking diseases. Correct diagnosis requires integration of clinical information and radiologic, laboratory, and pathological findings when available. We describe the radiologic findings of DLI, the roles of the findings in the management of patients with DLI, and the limitations of radiologic diagnosis.

摘要

药物性肺损伤(DLI)包含了各种各样的病理,每种病理都有其独特的影像学表现,因此不存在可用于确诊的特征性影像学发现。当怀疑发生 DLI 时,必须排除基础疾病、感染和类似疾病的进展。正确的诊断需要整合临床信息以及影像学、实验室和病理结果(如果有)。我们描述了 DLI 的影像学发现、这些发现对 DLI 患者管理的作用以及影像学诊断的局限性。

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