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Proteomics-directed cloning of circulating antiviral human monoclonal antibodies.

作者信息

Sato Shuji, Beausoleil Sean A, Popova Lana, Beaudet Jason G, Ramenani Ravi K, Zhang Xiaowu, Wieler James S, Schieferl Sandra M, Cheung Wan Cheung, Polakiewicz Roberto D

出版信息

Nat Biotechnol. 2012 Nov;30(11):1039-43. doi: 10.1038/nbt.2406.

DOI:10.1038/nbt.2406
PMID:23138294
Abstract
摘要

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Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants.记忆 B 细胞，但不是长寿浆细胞，具有针对病毒逃逸突变体的抗原特异性。
J Exp Med. 2011 Dec 19;208(13):2599-606. doi: 10.1084/jem.20110740. Epub 2011 Dec 12.
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B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.
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Pharmacol Ther. 2022 Dec;240:108233. doi: 10.1016/j.pharmthera.2022.108233. Epub 2022 Jun 20.
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An Immunoproteomic Survey of the Antibody Landscape: Insights and Opportunities Revealed by Serological Repertoire Profiling.免疫蛋白质组学调查抗体全景：血清免疫球蛋白文库分析揭示的见解和机遇
Front Immunol. 2022 Feb 1;13:832533. doi: 10.3389/fimmu.2022.832533. eCollection 2022.
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