SNBTS Tissue and Cells Directorate, Edinburgh, Scotland, UK.
Scott Med J. 2012 Nov;57(4):225-31. doi: 10.1258/smj.2012.012124.
Tissue banking in Scotland has developed significantly over the past 20 years or so. The range of issues procured has increased and so have their numbers. Initially, bone from live donors was the only tissue banked; later, tissues from multiorgan donors were procured; this was finally followed by the collection of tissues from donors following cardiac death. Bones, tendons, heart valves and skin are the main tissue types collected, stored and issued for clinical use. Much of our activity is based on identification of donors in two major accident and emergency departments followed by retrievals that take place in a dedicated mortuary by fully-trained staff. Tissues are released according to clinical need for Scottish patients and beyond. All of the tissue banking activity in Scotland takes place within the Scottish National Blood Transfusion Service, which is the preferred provider of tissues for Scottish patients. There is very close cooperation between our teams, the transplant teams and other clinical colleagues, including pathologists and anatomical technicians. The achievements in issue banking in Scotland are outlined along with the main clinical indications of the tissue procured. Diversification is now taking place into cellular therapy with the establishment of an islet processing programme and cell culturing techniques. The future is very exciting.
苏格兰的组织库在过去 20 年左右得到了显著发展。采集的组织范围扩大了,数量也增加了。最初,只有来自活体供者的骨组织被储存;后来,多器官供者的组织也被采集;最后,开始采集心死亡供者的组织。收集、储存和发放用于临床使用的主要组织类型有骨、肌腱、心脏瓣膜和皮肤。我们的大部分活动都是基于在两个主要的急症部门识别供者,然后由经过全面培训的工作人员在专门的太平间进行检索。根据苏格兰患者的临床需要发放组织,超出苏格兰范围的患者也可以申请。苏格兰的所有组织库活动都在苏格兰国家血液服务中心进行,该中心是苏格兰患者组织的首选提供者。我们的团队、移植团队和其他临床同事,包括病理学家和解剖技术人员之间有着非常密切的合作。本文概述了苏格兰在组织采集方面的成就,并介绍了采集组织的主要临床适应证。目前正在通过建立胰岛处理计划和细胞培养技术,向细胞治疗领域多元化发展。未来前景令人兴奋。