Unoki Eye Clinic, 1-7-15 Harara, Kagoshima, Kagoshima 890-0026, Japan.
Jpn J Ophthalmol. 2013 Jan;57(1):108-12. doi: 10.1007/s10384-012-0210-z. Epub 2012 Nov 9.
To report findings of optic disc melanocytoma (ODM) obtained using spectral domain optical coherence tomography (SD OCT), with special reference to the central retinal artery and vein surrounded by hyperreflective dots.
Retrospective review of five eyes of five patients with ODM. Demographic information, ophthalmic examination including best-corrected visual acuity, dilated funduscopic examination, and SD OCT images were evaluated.
Dome-shaped, darkly pigmented tumors were seen ophthalmoscopically in the optic discs of all eyes. On OCT, the first branches of the central retinal artery and/or vein were well defined as oblique sections of tubular structures with a perivascular distribution of hyperreflective dots in the elevated retina (nerve fiber layer) over the tumor. The portions where these vessels turn toward the retina were displaced more anteriorly than those of eyes without ODM. Hyperreflective dots of various sizes were also observed in elevated retinas over the tumors, which shadowed and obscured the subjacent tissue in all eyes.
SD OCT provides higher definition images of ODM relating to the branches of the central retinal artery/vein, revealing anterior displacement of vessels and perivascular distribution of hyperreflective dots that suggest melanophages and/or tumor cells or proteins and/or lipid deposits.
报告使用谱域光相干断层扫描（SD OCT）获得的视盘黑色素细胞瘤（ODM）的发现，特别参考被高反射点环绕的中央视网膜动脉和静脉。
回顾性分析 5 名 ODM 患者的 5 只眼。评估了人口统计学信息、最佳矫正视力的眼科检查、散瞳眼底检查和 SD OCT 图像。
所有眼睛的视盘均可见盘状、深色素性肿瘤。在 OCT 上，中央视网膜动脉和/或静脉的第一分支清晰可见，呈管状结构的斜切面，在肿瘤上方的抬高视网膜（神经纤维层）中可见血管周围分布的高反射点。这些血管朝向视网膜的部分比没有 ODM 的眼睛更靠前移位。在所有眼中，在肿瘤上方的抬高视网膜上还观察到各种大小的高反射点，这些点在所有眼中都遮挡和模糊了下方组织的阴影。
SD OCT 提供了与中央视网膜动脉/静脉分支有关的 ODM 的更高清晰度图像，显示了血管的前移位和血管周围分布的高反射点，提示黑色素细胞和/或肿瘤细胞或蛋白质和/或脂质沉积。
