Apinyawasisuk Supanut, McCannel Tara, Arnold Anthony C
Department of Ophthalmology, Chulalongkorn University, Bangkok, Thailand.
UCLA Stein Eye Institute, Los Angeles, CA, USA.
Ocul Oncol Pathol. 2017 Jul;3(2):142-148. doi: 10.1159/000453110. Epub 2016 Dec 14.
The aim of this paper was to compare the features of both the classic, darkly pigmented and the atypical, more lightly pigmented optic disc melanocytoma with those of pigmented choroidal lesions.
We analyzed the spectral-domain optical coherence tomography (SD-OCT) features of 9 eyes with optic disc melanocytoma and compared them with those of choroidal melanoma and nevus.
We identified 2 categories of SD-OCT findings in optic disc melanocytoma: (a) type 1, the typical, prominent, hyperpigmented lesion with SD-OCT findings of a hyperreflective, disorganized overlying retina and a posterior hyporeflective shadow, and (b) the less common, atypical, minimally pigmented type 2 lesion overlaid by a relatively well-organized retina that lacks a posterior hyporeflective shadow. Choroidal lesions were characterized by tumor confined beneath the clearly visible hyperreflective line of the photoreceptor and retinal pigment epithelium, with minimal disorganization of the overlying retina.
本文旨在比较典型的、色素沉着较深的视盘黑色素细胞瘤与非典型的、色素沉着较浅的视盘黑色素细胞瘤以及色素性脉络膜病变的特征。
我们分析了9例视盘黑色素细胞瘤患者眼部的频域光学相干断层扫描（SD-OCT）特征，并将其与脉络膜黑色素瘤和痣的特征进行比较。
我们在视盘黑色素细胞瘤中发现了两类SD-OCT表现：（a）1型，典型的、突出的色素沉着病变，SD-OCT表现为视网膜高反射、结构紊乱，后方有低反射阴影；（b）较罕见的非典型、色素沉着轻微的2型病变，其上覆盖的视网膜相对结构良好，无后方低反射阴影。脉络膜病变的特征是肿瘤局限于光感受器和视网膜色素上皮清晰可见的高反射线下方，上方视网膜结构紊乱轻微。
