Gaikwad Rohith, Kumaraswamy S V, Keerthi R
Dept. of Surgical Oncology, Tata Memorial Hospital, Mumbai, India ; Dept. of Surgical Oncology Head & Neck Services, Tata Memorial Hospital, Mumbai, India.
J Maxillofac Oral Surg. 2009 Mar;8(1):47-51. doi: 10.1007/s12663-009-0012-0. Epub 2009 Jun 10.
Owing to the aggressive nature of OKC's if one could stop or even reverse the growth of the cyst with a simple procedure like decompression, regardless of the histologic type, it would be an alternative to radical and disfiguring surgery.
Eight patients who were diagnosed with Odontogenic keratocyst of the mandible were chosen and the first stage of treatment being, insertion of the decompression stent into the most prominent or dependent part of the cystic cavity. Then based on assessment of regular second monthly OPG radiograph the second stage ie. Enucleation of the cyst and treatment of the cystic cavity with Carnoy's solution was carried out, when the size of the cystic cavity had decreased.
The radiographs of all the patients were analyzed at a two month interval and compared with the pre operative radiograph. The percentage of change in radiodensity of the lesion ranged from 35.15% to 66.16% with a mean decrease of 53.85%. This also indicated that the quantum of bone regeneration which occurred simultaneously and as observed during the cystectomy procedure was commendable.
Reduction of surgical morbidity while preserving anatomy and function, is the greatest advantage of decompression, however one should not forget the emphasis on the value of long term studies needed to be carried out with regular follow-up, to keep a check on those patients treated with decompression.
由于牙源性角化囊性瘤（OKC）具有侵袭性，如果能够通过像减压这样简单的操作来阻止甚至逆转囊肿的生长，而不考虑组织学类型，那么这将是根治性且会造成容貌毁损的手术的一种替代方法。
选取8例诊断为下颌骨牙源性角化囊性瘤的患者，治疗的第一阶段是将减压支架置入囊腔最突出或最低垂的部位。然后根据每月定期拍摄的口腔全景片（OPG）进行评估，当囊腔大小缩小时，进行第二阶段治疗，即囊肿摘除术并用卡诺氏液处理囊腔。
对所有患者的X线片每隔两个月进行分析，并与术前X线片进行比较。病变部位放射密度的变化百分比在35.15%至66.16%之间，平均降低了53.85%。这也表明在囊肿切除术中同时观察到的骨再生量是值得称赞的。
减压的最大优势在于在保留解剖结构和功能的同时降低手术并发症的发生率，然而不应忘记强调需要通过定期随访进行长期研究的重要性，以便对接受减压治疗的患者进行监测。
