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[开放置入三分支支架型人工血管行全主动脉弓重建与全主动脉置换联合带支架象鼻术治疗Stanford A型主动脉夹层的疗效比较]

[Efficacy comparison between total aortic arch reconstruction with open placement of triple-branched stent graft and total aortic replacement combined with stented elephant trunk implantation for patients with Stanford A aortic dissection].

作者信息

Shen Yun-hua, Yan Zhong-ya, Zhang Qing-chun, Lu Zhong, Zhu Zheng-yan, Cheng Guang-cun, Sun Yun, Zheng Li, Wu Yi-jun

机构信息

Department of Surgery, Anhui Medical University Provincial Hospital, Hefei, China.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 2012 Aug;40(8):676-80.

Abstract

OBJECTIVE

To compare the clinical efficacy between total aortic arch reconstruction with open triple-branched stent graft placement and total aortic replacement combined with stented elephant trunk implantation for patients with Stanford A aortic dissection.

METHODS

Patients with Stanford A aortic dissection treated with surgical treatment from January 2006 to May 2011 were included in this study. The patients were divided into two groups. Group I (n = 20) patients were treated by total arch replacement with stented elephant trunk procedure. Group II (n = 8) patients received open triple-branched stent graft placement. Echocardiography and aortic CT angiography were performed before and at 1 month after operation.

RESULTS

Age, gender and disease severity were similar between the 2 groups (all P > 0.05). Operation was successful in all 28 patients. Cardiopulmonary bypass time, aortic cross clamp time, circulation arrest time and duration of ventilator assisted breathing were significantly longer; postoperative drainage volume and blood transfusion volume were significantly larger and hospitalization cost was significantly higher in group I patients compared those in group II patients (all P < 0.05). One month after operation, the maximum internal diameter of aorta was smaller than pre-operation in both group I [(30.2 ± 3.1) mm vs. (42.5 ± 6.5) mm, P < 0.05] and group II [(31.5 ± 2.5) mm vs. (44.1 ± 7.3) mm, P < 0.05].

CONCLUSIONS

Short-term procedural success rate was similar between the two groups. The total aortic arch reconstruction with open triple-branched stent graft placement procedure is simpler, shortens the operation time, reduces the blood transfusion volume and is more cost-effective compared to the classical aortic arch operation.

摘要

目的

比较开放三分支支架型人工血管置入术全主动脉弓重建与全主动脉置换联合支架象鼻植入术治疗Stanford A型主动脉夹层患者的临床疗效。

方法

纳入2006年1月至2011年5月接受手术治疗的Stanford A型主动脉夹层患者。将患者分为两组。I组(n = 20)患者接受带支架象鼻术全弓置换术治疗。II组(n = 8)患者接受开放三分支支架型人工血管置入术。术前及术后1个月行超声心动图及主动脉CT血管造影检查。

结果

两组患者的年龄、性别及疾病严重程度相似(均P > 0.05)。28例患者手术均成功。与II组患者相比,I组患者的体外循环时间、主动脉阻断时间、循环停止时间及呼吸机辅助呼吸时间明显更长;术后引流量及输血量明显更大,住院费用明显更高(均P < 0.05)。术后1个月,I组[(30.2 ± 3.1)mm对(42.5 ± 6.5)mm,P < 0.05]和II组[(31.5 ± 2.5)mm对(44.1 ± 7.3)mm,P < 0.05]的主动脉最大内径均小于术前。

结论

两组的短期手术成功率相似。与经典主动脉弓手术相比,开放三分支支架型人工血管置入术全主动脉弓重建术操作更简单,缩短了手术时间,减少了输血量,且更具成本效益。

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