Aix Marseille Université, Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, WHO Collaborative Center for Rickettsioses and Other Arthropod Borne Bacterial Diseases, 27 bd Jean Moulin, 13385 Marseille Cedex 5, France.
Ticks Tick Borne Dis. 2012 Dec;3(5-6):361-3. doi: 10.1016/j.ttbdis.2012.10.018. Epub 2012 Nov 7.
African tick-bite fever (ATBF) caused by Rickettsia africae is a frequent cause of fever in returned travelers. Here, we used eschar swabs and/or eschar crust samples for the molecular diagnosis of ATBF in returned travelers. In 4 of 5 patients returning from South Africa, including 3 with negative serology, R. africae was identified by molecular tools targeting 2 different genes. The findings of this study highlight the usefulness of eschar swabs and/or eschar crust samples for the diagnosis of R. africae infection.
非洲蜱咬热（ATBF）是由非洲立克次体引起的，是返回旅行者发热的常见原因。在这里，我们使用焦痂拭子和/或焦痂痂皮样本对来自返回旅行者的 ATBF 进行分子诊断。在从南非返回的 5 名患者中的 4 名中，包括 3 名血清学阴性的患者，通过针对 2 个不同基因的分子工具鉴定出了非洲立克次体。本研究的结果强调了焦痂拭子和/或焦痂痂皮样本对诊断非洲立克次体感染的有用性。
