创伤患者送至城市一级创伤中心后,院外现场和转运时间及其与死亡率的关系。
Emergency medical services out-of-hospital scene and transport times and their association with mortality in trauma patients presenting to an urban Level I trauma center.
机构信息
Department of Emergency Medicine, UC Irvine School of Medicine, Orange, CA, USA.
出版信息
Ann Emerg Med. 2013 Feb;61(2):167-74. doi: 10.1016/j.annemergmed.2012.08.026. Epub 2012 Nov 9.
STUDY OBJECTIVE
We determine the association between emergency medical services (EMS) out-of-hospital times and mortality in trauma patients presenting to an urban Level I trauma center.
METHODS
We conducted a secondary analysis of a prospective cohort registry of trauma patients presenting to a Level I trauma center during a 14-year period (1996 to 2009). Inclusion criteria were patients sustaining traumatic injury who presented to an urban Level I trauma center. Exclusion criteria were extrication, missing or erroneous out-of-hospital times, and intervals exceeding 5 hours. The primary outcome was inhospital mortality. EMS out-of-hospital intervals (scene time and transport time) were evaluated with multivariate logistic regression.
RESULTS
There were 19,167 trauma patients available for analysis, with 865 (4.5%) deaths; 16,170 (84%) injuries were blunt, with 596 (3.7%) deaths, and 2,997 (16%) were penetrating, with 269 (9%) deaths. Mean age and sex for blunt and penetrating trauma were 34.5 years (68% men) and 28.1 years (90% men), respectively. Of those with Injury Severity Score less than or equal to 15, 0.4% died, and 26.1% of those with a score greater than 15 died. We analyzed the relationship of scene time and transport time with mortality among patients with Injury Severity Score greater than 15, controlling for age, sex, Injury Severity Score, and Revised Trauma Score. On multivariate regression of patients with penetrating trauma, we observed that a scene time greater than 20 minutes was associated with higher odds of mortality than scene time less than 10 minutes (odds ratio [OR] 2.90; 95% confidence interval [CI] 1.09 to 7.74). Scene time of 10 to 19 minutes was not significantly associated with mortality (OR 1.19; 95% CI 0.66 to 2.16). Longer transport times were likewise not associated with increased odds of mortality in penetrating trauma cases; OR for transport time greater than or equal to 20 minutes was 0.40 (95% CI 0.14 to 1.19), and OR for transport time 10 to 19 minutes was 0.64 (95% CI 0.35 to 1.15). For patients with blunt trauma, we did not observe any association between scene or transport times and increased odds of mortality.
CONCLUSION
In this analysis of patients presenting to an urban Level I trauma center during a 14-year period, we observed increased odds of mortality among patients with penetrating trauma if scene time was greater than 20 minutes. We did not observe associations between increased odds of mortality and out-of-hospital times in blunt trauma victims. These findings should be validated in an external data set.
研究目的
我们旨在确定在城市一级创伤中心就诊的创伤患者中,急救医疗服务(EMS)院外时间与死亡率之间的关系。
方法
我们对 14 年间(1996 年至 2009 年)在城市一级创伤中心就诊的创伤患者前瞻性队列登记进行了二次分析。纳入标准为发生创伤性损伤并就诊于城市一级创伤中心的患者。排除标准为解救、院外时间缺失或错误以及间隔超过 5 小时。主要结局是院内死亡率。使用多变量逻辑回归评估 EMS 院外时间(现场时间和转运时间)。
结果
共有 19167 名创伤患者可进行分析,其中 865 名(4.5%)死亡;16170 名(84%)损伤为钝性,其中 596 名(3.7%)死亡,2997 名(16%)为穿透性,其中 269 名(9%)死亡。钝性和穿透性创伤的平均年龄和性别分别为 34.5 岁(68%为男性)和 28.1 岁(90%为男性)。损伤严重度评分(ISS)≤15 的患者中,死亡率为 0.4%,ISS>15 的患者中死亡率为 26.1%。我们分析了 ISS 评分大于 15 的患者中,现场时间和转运时间与死亡率的关系,同时控制了年龄、性别、ISS 和修订创伤评分。在穿透性创伤患者的多变量回归分析中,我们观察到现场时间大于 20 分钟与死亡率较高相关,而现场时间小于 10 分钟则与死亡率较低相关(比值比[OR]2.90;95%置信区间[CI]1.09 至 7.74)。现场时间为 10 至 19 分钟与死亡率无显著相关性(OR 1.19;95%CI0.66 至 2.16)。较长的转运时间也与穿透性创伤病例的死亡率增加无关;转运时间大于或等于 20 分钟的 OR 为 0.40(95%CI0.14 至 1.19),转运时间 10 至 19 分钟的 OR 为 0.64(95%CI0.35 至 1.15)。对于钝性创伤患者,我们未观察到现场或转运时间与死亡率增加之间存在任何关联。
结论
在对 14 年间在城市一级创伤中心就诊的患者进行的这项分析中,我们观察到,如果现场时间大于 20 分钟,穿透性创伤患者的死亡风险增加。我们没有观察到钝性创伤受害者的死亡率与院外时间之间存在关联。这些发现应在外部数据集进行验证。