Rodway Megan, Vance Annette, Watters Amany, Lee Helen, Bos Elske, Kaplan Bonnie J
Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada.
BMJ Case Rep. 2012 Nov 9;2012:bcr2012007213. doi: 10.1136/bcr-2012-007213.
Psychosis is difficult to treat effectively with conventional pharmaceuticals, many of which have adverse long-term health consequences. In contrast, there are promising reports from several research groups of micronutrient treatment (vitamins, minerals, amino acids and essential fatty acids) of mood, anxiety and psychosis symptoms using a complex formula that appears to be safe and tolerable. We review previous studies using this formula to treat mental symptoms, and present an 11-year-old boy with a 3-year history of mental illness whose parents chose to transition him from medication to micronutrients. Symptom severity was monitored in three clusters: anxiety, obsessive compulsive disorder and psychosis. Complete remission of psychosis occurred, and severity of anxiety and obsessional symptoms decreased significantly (p<0.001); the improvements are sustained at 4-year follow-up. A cost comparison revealed that micronutrient treatment was <1% of his inpatient mental healthcare. Additional research on broad-spectrum micronutrient treatment is warranted.
精神病难以用传统药物有效治疗,其中许多药物会对长期健康产生不良后果。相比之下,几个研究小组有一些很有前景的报告,称使用一种似乎安全且耐受性良好的复合配方,用微量营养素(维生素、矿物质、氨基酸和必需脂肪酸)治疗情绪、焦虑和精神病症状。我们回顾了以往使用该配方治疗精神症状的研究,并介绍了一名患有3年精神疾病史的11岁男孩,其父母选择让他从药物治疗转为微量营养素治疗。对症状严重程度进行了三个方面的监测:焦虑、强迫症和精神病。精神病症状完全缓解,焦虑和强迫症状的严重程度显著降低(p<0.001);在4年的随访中,这些改善持续存在。成本比较显示,微量营养素治疗的费用不到他住院精神保健费用的1%。有必要对广谱微量营养素治疗进行更多研究。