Bouissou H, de Graeve J, Thiers J C, Solera M L, Valdiguie P
Biomedicine. 1979 Dec;31(8):236-9.
The present report concerns the biochemical and anatomo-pathological study of the skin and the plasma lipoprotein fractions in a young population (average age : 22 +/- 1.5 years). The levels of cutaneous cholesterol and the ratio HDL cholesterol/total cholesterol are closely linked even through the histological structure of the skin is still normal; the level of cutaneous cholesterol giving a good indication of the degree of vascular ageing. The observations confirm the usefulness of measuring these two parameters in the detection of early atherosclerosis.
本报告涉及对年轻人群(平均年龄:22±1.5岁)皮肤及血浆脂蛋白组分的生化和解剖病理学研究。即使皮肤的组织结构仍属正常,皮肤胆固醇水平与高密度脂蛋白胆固醇/总胆固醇比值仍密切相关;皮肤胆固醇水平能很好地反映血管老化程度。这些观察结果证实了在早期动脉粥样硬化检测中测量这两个参数的实用性。