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Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.
EMBO Rep. 2012 Dec;13(12):1087-94. doi: 10.1038/embor.2012.164. Epub 2012 Nov 13.
2
PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling.
Curr Biol. 2013 Nov 4;23(21):2185-90. doi: 10.1016/j.cub.2013.09.017. Epub 2013 Oct 24.
3
Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype.
Mol Biol Cell. 2016 Dec 15;27(25):4033-4042. doi: 10.1091/mbc.E16-08-0564. Epub 2016 Oct 26.
4
The HECT domain ligase itch ubiquitinates endophilin and localizes to the trans-Golgi network and endosomal system.
J Biol Chem. 2004 Mar 19;279(12):11471-9. doi: 10.1074/jbc.M309934200. Epub 2003 Dec 18.
6
Lipid and peptide control of phosphatidylinositol 4-kinase IIalpha activity on Golgi-endosomal Rafts.
J Biol Chem. 2006 Feb 17;281(7):3757-63. doi: 10.1074/jbc.M506527200. Epub 2005 Oct 25.

引用本文的文献

1
Phosphatidylinositol 4-phosphate; A minor lipid with multiple personalities.
Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Jun;1870(5):159615. doi: 10.1016/j.bbalip.2025.159615. Epub 2025 Apr 20.
2
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The Role of HECT-Type E3 Ligase in the Development of Cardiac Disease.
Int J Mol Sci. 2021 Jun 4;22(11):6065. doi: 10.3390/ijms22116065.
5
Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.
Autophagy. 2021 Nov;17(11):3690-3706. doi: 10.1080/15548627.2021.1891848. Epub 2021 Mar 9.
7
ITCH as a potential therapeutic target in human cancers.
Semin Cancer Biol. 2020 Dec;67(Pt 2):117-130. doi: 10.1016/j.semcancer.2020.03.003. Epub 2020 Mar 10.
8
Phosphatidylinositol Kinases and Phosphatases in .
Front Cell Infect Microbiol. 2019 Jun 6;9:150. doi: 10.3389/fcimb.2019.00150. eCollection 2019.
9
A SEPT1-based scaffold is required for Golgi integrity and function.
J Cell Sci. 2019 Feb 1;132(3):jcs225557. doi: 10.1242/jcs.225557.

本文引用的文献

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The spatial and temporal organization of ubiquitin networks.
Nat Rev Mol Cell Biol. 2011 May;12(5):295-307. doi: 10.1038/nrm3099. Epub 2011 Mar 30.
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Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt.
EMBO J. 2010 Jul 7;29(13):2114-25. doi: 10.1038/emboj.2010.100. Epub 2010 May 21.
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Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling.
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Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities.
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Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl.
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Physiological functions of the HECT family of ubiquitin ligases.
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Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
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Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase II{alpha}.
J Biol Chem. 2009 Apr 10;284(15):9994-10003. doi: 10.1074/jbc.M900724200. Epub 2009 Feb 11.
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Function and dysfunction of the PI system in membrane trafficking.
EMBO J. 2008 Oct 8;27(19):2457-70. doi: 10.1038/emboj.2008.169. Epub 2008 Sep 11.
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Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.
Science. 2008 Sep 5;321(5894):1350-3. doi: 10.1126/science.1160741.

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