他汀类药物治疗多囊卵巢综合征的证据。
Evidence for statin therapy in polycystic ovary syndrome.
机构信息
Stephen L. Atkin Diabetes, Endocrinology and Metabolism, Hull York Medical School, Hull, UK.
出版信息
Ther Adv Endocrinol Metab. 2010 Feb;1(1):15-22. doi: 10.1177/2042018810367984.
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group that is associated with increased cardiovascular risk. In addition to its lipid-lowering effects, statin therapy has shown been shown to have beneficial pleiotropic effects that may contribute to their reduction in cardiovascular morbidity and mortality. In this review, the effect of statins on PCOS is discussed with reference to the underlying potential mechanism of action.
摘要
多囊卵巢综合征（PCOS）是育龄妇女常见的内分泌疾病，与心血管风险增加有关。除了降低血脂的作用外，他汀类药物治疗还显示出有益的多效作用，这可能有助于降低心血管发病率和死亡率。本文讨论了他汀类药物对 PCOS 的影响，并参考了潜在的作用机制。
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