揭示战争“无形之伤”的窗口：创伤后应激障碍的参战退伍军人 REM 睡眠的功能神经影像学。
A window into the invisible wound of war: functional neuroimaging of REM sleep in returning combat veterans with PTSD.
机构信息
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
出版信息
Psychiatry Res. 2013 Feb 28;211(2):176-9. doi: 10.1016/j.pscychresns.2012.05.007. Epub 2012 Nov 11.
Abstract
Relative regional cerebral metabolic rate of glucose in rapid eye movement (REM) sleep and wakefulness was explored in combat veterans with and without posttraumatic stress disorder PTSD, using positron emission tomography. Hypermetabolism in brain regions involved in arousal regulation, fear responses, and reward processing persist during REM sleep in combat veterans with PTSD.
摘要
采用正电子发射断层扫描技术，研究了创伤后应激障碍（PTSD）和无 PTSD 的参战退伍军人在快速眼动（REM）睡眠和觉醒状态下大脑局部葡萄糖代谢率的相对变化。研究发现，患有 PTSD 的参战退伍军人在 REM 睡眠期间，与觉醒调节、恐惧反应和奖励处理相关的大脑区域持续出现代谢亢进。
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