Centre for Ecosystem Management, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA 6027, Australia.
Int J Hyg Environ Health. 2013 Nov;216(6):641-4. doi: 10.1016/j.ijheh.2012.10.002. Epub 2012 Nov 11.
Bisphenol A is a chemical that is present in a number of products and types of food packaging. Prenatal exposure to bisphenol A may cause behavioural changes in young children. The aim of this study was to investigate exposure to bisphenol A in pregnant Australian women as a surrogate of neonatal exposure. First morning void urine samples were collected from 26 pregnant women at around week 38 of gestation. Bisphenol A was detectable in 85% of the samples analysed. The median concentration in this group of women was 2.41μg/L with a range of <LOD - 5.66μg/L. Women experiencing their first pregnancy had slightly higher urinary bisphenol A concentrations, as did women with a pre-pregnancy BMI of <25, however these relationships did not reach significance. This study provides the first information on bisphenol A exposure in Australia and reveals that pregnant women have measured biological concentrations of urinary bisphenol A similar to those reported for pregnant women in other developed countries. Given the potential impacts of prenatal bisphenol A exposure, further research in this area is warranted.
双酚 A 是一种存在于许多产品和食品包装类型中的化学物质。产前暴露于双酚 A 可能导致幼儿行为发生变化。本研究旨在调查澳大利亚孕妇双酚 A 的暴露情况，以作为新生儿暴露的替代指标。在妊娠第 38 周左右，从 26 名孕妇中采集了第一次晨尿样本。在分析的样本中，85%可检测到双酚 A。这组妇女的中位数浓度为 2.41μg/L，范围为<LOD-5.66μg/L。首次怀孕的女性尿液中双酚 A 浓度略高，孕前 BMI<25 的女性也是如此，但这些关系没有达到显著水平。本研究提供了澳大利亚双酚 A 暴露的第一手资料，并表明孕妇尿液中双酚 A 的生物浓度与其他发达国家孕妇报告的浓度相似。鉴于产前双酚 A 暴露的潜在影响，该领域的进一步研究是有必要的。
