Department of Surgical and Medical Critical Care, Division of Neonatology, Careggi University Hospital of Florence, Viale Morgagni, 85, 50134, Florence, Italy.
Eur J Pediatr. 2013 Mar;172(3):331-6. doi: 10.1007/s00431-012-1885-3. Epub 2012 Nov 14.
We carried out a survey of current practices of neonatal respiratory support in neonatal intensive care units (NICUs) in Italy with the aim of comparing the current reality with evidence from the literature. We sent a questionnaire by email to the 103 level III neonatal units in Italy. There was a 61 % (73/120) response rate to the questionnaire. We found that synchronized intermittent positive pressure ventilation is mostly used in infants in the acute phase of respiratory distress syndrome (RDS), while the majority of the units prefer volume-targeted ventilation for those in the weaning phase. Nasal continuous positive airway pressure is the most commonly used non-invasive mode of respiratory support, both in the acute and post-extubation phase of RDS. Surfactant is mainly given as rescue treatment. Infants receive caffeine before extubation and analgesia under mechanical ventilation, while post-natal steroids are given after the first week of life in the majority of the units. In conclusion, respiratory support strategies in Italian NICUs are frequently evidence-based. However, since there are areas where this does not occur, we suggest that focused interventions take place on these areas to help improve clinical practice and increase their adherence to evidence-based medical criteria.
我们对意大利新生儿重症监护病房(NICU)中新生儿呼吸支持的当前实践进行了调查,旨在将当前的实际情况与文献中的证据进行比较。我们通过电子邮件向意大利的 103 个三级新生儿单位发送了一份问卷。对问卷的回复率为 61%(73/120)。我们发现,同步间歇正压通气主要用于呼吸窘迫综合征(RDS)急性发作期的婴儿,而大多数单位更喜欢在撤机阶段使用容量目标通气。鼻持续气道正压通气是 RDS 急性和拔管后阶段最常用的无创呼吸支持模式。表面活性剂主要作为抢救治疗。大多数单位在婴儿拔管前给予咖啡因,并在机械通气时给予镇痛,而在大多数单位中,在生命的第一周后给予产后类固醇。总之,意大利 NICU 的呼吸支持策略经常是基于证据的。然而,由于存在一些没有发生的情况,我们建议在这些领域进行有针对性的干预,以帮助改善临床实践并增加对基于证据的医疗标准的依从性。