Kudrna K, Andrlíková J, Smíd A, Stipl Z
Czech Med. 1979;2(3):141-7.
Rosette forming cells (RFC) were evaluated in the peripheral blood of healthy persons, patients with lung cancer and chronic bronchitis. Simultaneously the levels of RFC in persons with and without radiation exposure were compared. Two types of rosettes were enumerated: 1) lymphocytes binding 1 or 2 sheep red blood cells (SRBC), 2) lymphocytes binding 3 or more SRBC. Then the sum of both types was calculated. The patients with lung cancer were divided according to the TNM classification and histological types. The relative and absolute numbers of RFC in 1 microliter of peripheral blood proved depressed capacity of peripheral T-lymphocytes to form rosettes not only in patients with cancer or chronic bronchitis but also in controls with radiation exposure. Furthermore, there was established that the control group with radiation exposure was not different from the patients with cancer or chronic bronchitis.
对健康人、肺癌患者和慢性支气管炎患者的外周血中的玫瑰花结形成细胞（RFC）进行了评估。同时，比较了有辐射暴露和无辐射暴露人群的RFC水平。计数了两种类型的玫瑰花结：1）结合1个或2个绵羊红细胞（SRBC）的淋巴细胞，2）结合3个或更多SRBC的淋巴细胞。然后计算两种类型的总和。肺癌患者根据TNM分类和组织学类型进行分组。结果表明，每微升外周血中RFC的相对和绝对数量证实，不仅癌症或慢性支气管炎患者，而且有辐射暴露的对照组外周T淋巴细胞形成玫瑰花结的能力均降低。此外，还确定有辐射暴露的对照组与癌症或慢性支气管炎患者没有差异。
