Behinaein Sepideh, Chettle David R, Egden Lesley M, McNeill Fiona E, Norman Geoff, Richard Norbert, Stever Susan
Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
J Environ Monit. 2012 Dec;14(12):3267-75. doi: 10.1039/c2em30652b. Epub 2012 Nov 14.
494 smelter employees from New Brunswick participated in a bone lead survey conducted by McMaster University in 2008, using the four element "clover-leaf" geometry germanium detector system. The employees were measured at two different bone sites, tibia and calcaneus, each measurement lasting 30 minutes. Scattered photons, including Pb X-rays, were collected by the germanium detectors located behind the ¹⁰⁹Cd source. A strong positive correlation was observed between tibia and calcaneus lead concentrations. Having been provided with blood lead levels, a cumulative blood lead index (CBLI) was generated. The employees were classified into four groups based on their date of hire, and their CBLI levels were compared to their tibia and calcaneus lead concentrations in the different groups. The slopes of bone Pb versus CBLI varied amongst groups, with those hired earliest showing the steepest slopes. This could be taken to imply a non-linearity in the uptake of Pb by bone from blood. In this paper, the association of the bone lead concentrations versus CBLI has been expressed by a polynomial function for the whole group of employees.
494名来自新不伦瑞克省的冶炼厂员工参与了麦克马斯特大学于2008年开展的一项骨铅调查，该调查使用了四元素“三叶草叶形”几何结构锗探测器系统。对员工的两个不同骨骼部位——胫骨和跟骨进行了测量，每次测量持续30分钟。包括铅X射线在内的散射光子由位于¹⁰⁹镉源后方的锗探测器收集。胫骨和跟骨中的铅浓度之间观察到了很强的正相关性。在获得血铅水平后，生成了累积血铅指数（CBLI）。根据雇佣日期将员工分为四组，并比较了不同组中他们的CBLI水平与胫骨和跟骨的铅浓度。不同组中骨铅与CBLI的斜率各不相同，入职最早的那些组斜率最陡。这可能意味着骨骼从血液中摄取铅存在非线性关系。在本文中，对于全体员工，骨铅浓度与CBLI之间的关联已用多项式函数表示。
