Puerta Roldán Patricia, Rodríguez Rodríguez Rodrigo, Bagué Rossell Silvia, de Juan Delago Manel, Molet Teixidó Joan
Servicio de Neurocirugía, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Neurocirugia (Astur). 2013 Jul-Aug;24(4):178-82. doi: 10.1016/j.neucir.2012.09.002. Epub 2012 Nov 13.
Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of low-grade fibrosarcoma, with specific histological and immunohistochemical features and a poor prognosis. We report a case of SEF of the paravertebral column in a 49-year old male who presented a paraspinal mass with extension into the L4-L5 neural foramen and invasion of the L5 nerve root. Histology of the tumourectomy specimen and its immunohistochemical study led to the diagnosis of SEF. This case was particularly unusual due to its paravertebral column location and, despite its low grade, illustrates the malignant potential of SEF.
硬化性上皮样纤维肉瘤(SEF)是低级别纤维肉瘤的一种罕见变体,具有特定的组织学和免疫组化特征,预后较差。我们报告一例49岁男性脊柱旁SEF病例,该患者表现为椎旁肿块,延伸至L4-L5神经孔并侵犯L5神经根。肿瘤切除标本的组织学检查及其免疫组化研究确诊为SEF。该病例因其脊柱旁位置而尤为特殊,尽管级别较低,但仍显示出SEF的恶性潜能。