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[超高剂量电离辐射对大鼠脑组织三磷酸腺苷含量的影响]

[The effect of ionizing radiation at superhigh dosages on the ATP content in the rat brain].

作者信息

Kormer Z S, Rozhdestvenskiĭ L M

出版信息

Radiobiologiia. 1990 Jan-Feb;30(1):46-9.

PMID:2315459
Abstract

The ATP content of rat brain was shown to decrease considerably (20-60%) during the first minutes following high-energy electron irradiation with doses of 300 and 500 Gy. A transient nature of changes and a more pronounced decrease in ATP with increasing radiation dose and manifest neurologic disturbances indicate that the energy metabolism is involved in the pathogenesis of early neurologic disturbances in animals.

摘要

结果显示,用300和500戈瑞的高能电子辐射大鼠脑部后的最初几分钟内,其ATP含量显著下降(20%-60%)。变化具有短暂性,且随着辐射剂量增加ATP下降更明显,同时伴有明显的神经功能障碍,这表明能量代谢参与了动物早期神经功能障碍的发病机制。

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