Varga B, Zsolnai B, Bernard A
Gynecol Obstet Invest. 1979;10(2-3):81-7. doi: 10.1159/000299921.
The effect of fenoterol and norepinephrine was studied on the vascular resistance of in vitro perfused human ovary. It was found that the beta-adrenergic stimulant fenoterol causes vasodilatation, whereas the alpha-adrenergic stimulant norepinephrine elicits vasoconstriction in the arterial vascular bed of the ovary showing the role of adrenergic mechanism in the regulation of ovarian blood flow. It was supposed that therapeutical administration of beta-mimetic drugs leads to the elevation of ovarian blood flow, which may have special importance in the case of corpus luteum insufficiency.
研究了非诺特罗和去甲肾上腺素对体外灌注人卵巢血管阻力的影响。结果发现，β-肾上腺素能兴奋剂非诺特罗可引起血管舒张，而α-肾上腺素能兴奋剂去甲肾上腺素则引起卵巢动脉血管床血管收缩，这表明肾上腺素能机制在调节卵巢血流中发挥作用。据推测，β-拟交感神经药物的治疗性给药会导致卵巢血流增加，这在黄体功能不全的情况下可能具有特殊重要性。
