Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA.
Occup Environ Med. 2013 Feb;70(2):120-5. doi: 10.1136/oemed-2011-100569. Epub 2012 Nov 15.
We examined the association between household solid fuel exposure and lung function in a densely populated district in urban Shanghai, China.
Spirometry was performed in 12 506 subjects, aged 18 and over, residing in the Putuo District in Shanghai, China, in a cross-sectional survey. Exposure to solid fuel use at home was assessed by an administered questionnaire, estimating duration and total amount of solid fuel use at home during the lifetime.
After adjusting for confounders, the subjects with exposure to household solid fuel had a 1.3% (95% CI 0.57 to 2.02) decrease in forced expiratory volume in 1 s (FEV(1)) percent predicted and 3.5% (95% CI 2.74 to 4.18) decrease in forced vital capacity (FVC) percent predicted, respectively. Trends towards decreased pulmonary function measures were seen for longer duration and greater amount of household fuel use at home, in the highest compared with lowest tertile (p values for trend <0.001). We observed decrease in FEV(1) and FVC percent predicted across increase in tertile of body mass index in association with in-home solid fuel exposure.
This study suggests that in-home solid fuel exposure is associated with reduced lung function in an urban population.
在中国上海一个人口稠密的城区，我们研究了家庭固体燃料暴露与肺功能之间的关系。
在横断面调查中，对居住在中国上海普陀区的 12506 名 18 岁及以上的成年人进行了肺量测定。通过问卷调查评估家庭固体燃料的使用暴露情况，估计一生中在家中使用固体燃料的时间和总量。
在校正混杂因素后，与暴露于家用固体燃料的受试者相比，其用力呼气量（FEV1）预计值降低了 1.3%（95%可信区间为 0.57 至 2.02），用力肺活量（FVC）预计值降低了 3.5%（95%可信区间为 2.74 至 4.18）。在家中使用固体燃料的时间越长、数量越多，与最低三分位相比，肺功能指标的下降趋势越明显（趋势检验 p 值<0.001）。我们观察到，与在家中固体燃料暴露相关的体质指数三分位增加与 FEV1 和 FVC 预计值的下降有关。
本研究表明，家庭固体燃料暴露与城市人群的肺功能下降有关。
