De Luca Jacqueline F, Lee Yun Sun, Johnson Douglas
University of Hawai'i Transitional Residency Program, Honolulu, HI, USA.
Hawaii J Med Public Health. 2012 Nov;71(11):324-5.
Immunosuppressant medications for Inflammatory Bowel Disease can help with both symptoms and disease progression. However, like immunosuppressants used in transplant patients, they are now suspect of contributing to nonmelenoma skin cancer (NMSC). Presented is a case of a 57-year-old Jewish man with Crohn's Disease who was diagnosed with a total of 84 NMSCs. We hope to elucidate the risk of immunosuppressants, particularly the thiopurines, on the development of NMSC.
用于治疗炎症性肠病的免疫抑制药物对症状缓解和疾病进展均有帮助。然而，与用于移植患者的免疫抑制剂一样，它们现在被怀疑会导致非黑素瘤皮肤癌（NMSC）。本文介绍了一例57岁患克罗恩病的犹太男性病例，该患者共被诊断出84处非黑素瘤皮肤癌。我们希望阐明免疫抑制剂，尤其是硫唑嘌呤，在非黑素瘤皮肤癌发生中的风险。
