Department of Internal Medicine, University of Minnesota, Minneapolis, MN, USA.
Division of Gastroenterology, University of California San Francisco, San Francisco, CA, USA.
Gastroenterol Clin North Am. 2017 Sep;46(3):515-529. doi: 10.1016/j.gtc.2017.05.006.
Crohn's disease (CD) is a chronic inflammatory disease that confers a higher risk of cancer than in the general population. New, large, population-based studies in the past decade show that patients with CD are at higher risk of colorectal, small bowel, melanoma, and cervical cancer. Patients who use thiopurines are at additional risk of development of lymphoma and nonmelanoma skin cancer. Preventive surveillance for cancers of the colorectum, skin, and uterine cervix is advised.
克罗恩病（CD）是一种慢性炎症性疾病，其癌症风险高于普通人群。过去十年中的新的、大型的基于人群的研究表明，CD 患者罹患结直肠、小肠、黑色素瘤和宫颈癌的风险更高。使用硫嘌呤的患者发生淋巴瘤和非黑色素瘤皮肤癌的风险增加。建议对结直肠、皮肤和子宫颈的癌症进行预防性监测。
