School of Medicine, University of St Andrews, Fife, Scotland, UK.
Community Dent Oral Epidemiol. 2013 Aug;41(4):289-308. doi: 10.1111/cdoe.12014. Epub 2012 Nov 16.
Obesity and dental caries have become increasingly prevalent challenges to public health. Research results into the relationship between obesity and dental caries in children have been mixed and inconclusive. The aim of this review and meta-analysis was to provide evidence to quantify the relationship between obesity and dental caries in children using a systematic approach.
A systematic search for papers between 1980 and 2010 addressing childhood obesity and dental caries was conducted and a random effects model meta-analysis applied.
Fourteen papers met the selection criteria. Overall, a significant relationship between childhood obesity and dental caries (effect size = 0.104, P = 0.049) was found. When analysed by dentition type (primary versus permanent), there was a nonsignificant association of obesity and dental caries in permanent and primary dentitions, yet on accounting only for standardized definitions for assessment of child obesity using body mass index, a strong significant relationship was evident in children with permanent dentitions. Moderating for study country of origin (newly 'industrialized' versus industrialized) showed a significant relationship between obesity and dental caries in children from industrialized but not newly industrialized countries. Cofactors such as age and socioeconomic class were significant moderators.
Future analysis should investigate these confounding variables, helping shape the future of obesity management programmes and oral health interventions, through determining common risk factors.
肥胖和龋齿已成为公共卫生领域日益严峻的挑战。有关儿童肥胖与龋齿之间关系的研究结果喜忧参半，尚无定论。本综述和荟萃分析旨在采用系统方法提供定量证据，以阐明儿童肥胖与龋齿之间的关系。
对 1980 年至 2010 年间涉及儿童肥胖和龋齿的论文进行了系统检索，并应用随机效应模型荟萃分析。
符合选择标准的论文有 14 篇。总体而言，儿童肥胖与龋齿之间存在显著关系（效应量=0.104，P=0.049）。按牙列类型（乳牙与恒牙）分析，肥胖与恒牙和乳牙龋齿之间无显著关联，但仅考虑使用体质量指数评估儿童肥胖的标准化定义时，恒牙龋齿与肥胖的关联具有统计学意义。按研究来源国（新兴工业化国家与工业化国家）进行调节分析显示，工业化国家儿童肥胖与龋齿之间存在显著关联，但新兴工业化国家无此关联。年龄和社会经济阶层等混杂因素是显著的调节因素。
未来的分析应调查这些混杂变量，通过确定共同的危险因素，为肥胖管理计划和口腔健康干预措施的未来发展提供依据。
