Zhu Li-ming, Fang Xiu-cai, Liu Shi, Zhang Jun, Li Zhao-shen, Hu Pin-jin, Gao Jun, Xin Hai-wei, Ke Mei-yun
Department of Gastroenterology, Chinese Academy of Medical Sciences, Beijing, China.
Zhonghua Yi Xue Za Zhi. 2012 Aug 28;92(32):2243-6.
To survey the emotional and sleeping status of patients with chronic constipation (CC) and analyze the relationship between psychological status and constipated symptoms.
From January 2009 to April 2010, 5 centers and 25 stratified hospitals were selected as the representatives of different regions of mainland China. The CC questionnaires including constipated symptoms, emotional and sleeping status, previous treatments and self-reported impact of constipation on health status, etc. Questionnaires were completed by well-trained physicians or investigators during face-to-face interviews. CC was diagnosed in accordance with the Rome III criteria.
A total of 909 valid questionnaires analyzed. There were 258 males and 651 females with a mean age of (49 ± 19) years. 41.5% (377 cases) reported "tense feelings" and 38.3% (348 cases) "felt downcast" over the past 3 months. The patients feeling tense and(or) downcast "frequently" and "most of time" were around 11.3% (103 cases) and 9.4% (85 cases). And 43.8% (398 cases) patients reported sleeping disorders over the past 3 months. Regional differences existed in the comorbidities of psychological and sleeping disorders in CC patients, especially in those from tertiary hospitals. And it was the highest in Beijing area for tense feelings and downcast. The sleeping disorders were the most common in the patients from secondary hospitals, of which 66.1% (37/56) and 65.0% (39/60) were from Wuhan and Xi'an respectively. They were higher than Beijing and Guangzhou (39.7% (23/58), 29.0% (9/31), all P = 0.001). The patients from rural primary clinics suffered more sleeping disorders than those from urban primary cares (P = 0.026). About 35.0% (318 cases) and 28.4% (258 cases) patients reported their constipation was related with emotional and sleeping disorders. The comorbidities of psychological and sleeping disorders were more common in severe constipated patients than mild and moderate counterparts and resulted in more hospital visits (both P = 0.000).
The CC patients often have the comorbidities of psychological and sleeping disorders with regional differences. The patients from the hospitals at various levels may present different spectrums of comorbidities of psychological and sleeping disorders. And the severity of CC influences the moods, sleeps and hospital visits.
调查慢性便秘（CC）患者的情绪及睡眠状况，并分析心理状态与便秘症状之间的关系。
2009年1月至2010年4月，选取5个中心的25家分层医院作为中国大陆不同地区的代表。CC问卷包括便秘症状、情绪及睡眠状况、既往治疗情况以及患者自报便秘对健康状况的影响等。问卷由训练有素的医生或调查人员在面对面访谈时完成。CC根据罗马III标准进行诊断。
共分析909份有效问卷。其中男性258例，女性651例，平均年龄（49±19）岁。41.5%（377例）患者报告在过去3个月内有“紧张情绪”，38.3%（348例）“情绪低落”。“经常”和“大部分时间”感到紧张和（或）情绪低落的患者分别约为11.3%（103例）和9.4%（85例）。43.8%（398例）患者报告在过去3个月内有睡眠障碍。CC患者心理和睡眠障碍的合并症存在地区差异，尤其是在三级医院患者中。北京地区紧张情绪和情绪低落的发生率最高。二级医院患者睡眠障碍最为常见，其中武汉和西安的患者分别为66.1%（37/56）和65.0%（39/60）。高于北京和广州（39.7%（23/58），29.0%（9/31），P均=0.001）。农村基层诊所的患者比城市基层医疗的患者睡眠障碍更多（P = 0.026）。约35.0%（318例）和28.4%（258例）患者报告其便秘与情绪和睡眠障碍有关。严重便秘患者心理和睡眠障碍的合并症比轻度和中度便秘患者更常见，且就诊次数更多（P均=0.000）。
CC患者常合并心理和睡眠障碍，且存在地区差异。不同级别医院的患者心理和睡眠障碍合并症谱可能不同。CC的严重程度影响情绪、睡眠及就诊次数。
