Li Shu-ben, He Jian-xing, Li Shi-yue, Chen Han-zhang, Yin Wei-qiang, Cheng Xiang-yang, Liu Jun, Chen Yu
The First Affiliated Hospital of Guangzhou Medical College, Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China.
Zhonghua Zhong Liu Za Zhi. 2012 Aug;34(8):613-5. doi: 10.3760/cma.j.issn.0253-3766.2012.08.012.
To evaluate the clinical value of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) biopsy for diagnosis of PET-CT positive mediastinal lymph nodes.
One hundred and twenty-six patients with lung cancer undergoing both PET-CT scanning and EBUS-TBNA biopsy in the First Affiliated Hospital of Guanzhou Medical College from July 2008 to August 2010 were included in this study. There were 89 male and 37 female patients with a mean age of 56.3 years (range 34 to 81 years). (18)FDG-PET was considered positive in mediastinal nodes if the PET-CT reported hypermetabolic activity consistent with malignant disease (standardized uptake value > 2.5). All of the patients were clinically followed up.
Among the 126 patients, 185 stations of lymph nodes were punctured. The mean diameter of the nodes was 13.6 mm and the range was 6 - 23 mm. There were no procedural complications. The diagnostic accuracy, sensitivity, and specificity of EBUS-TBNA were 95.7%, 95.7%, and 100%, respectively.
EBUS-TBNA is a minimally invasive, highly effective and accurate, practical and safe procedure for diagnosis of PET-CT positive mediastinal lymph nodes.
评估支气管内超声引导针吸活检术（EBUS-TBNA）对PET-CT检查呈阳性的纵隔淋巴结的诊断价值。
本研究纳入了2008年7月至2010年8月期间在广州医学院第一附属医院接受PET-CT扫描及EBUS-TBNA活检的126例肺癌患者。其中男性89例，女性37例，平均年龄56.3岁（范围34至81岁）。若PET-CT报告纵隔淋巴结有与恶性疾病相符的高代谢活性（标准化摄取值>2.5），则(18)FDG-PET被视为阳性。所有患者均进行临床随访。
126例患者共穿刺185个淋巴结站。淋巴结平均直径为13.6mm，范围为6 - 23mm。无操作相关并发症。EBUS-TBNA的诊断准确率、敏感性和特异性分别为95.7%、95.7%和100%。
EBUS-TBNA是诊断PET-CT阳性纵隔淋巴结的一种微创、高效、准确、实用且安全的方法。
