Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Clin Pharmacol Ther. 2012 Dec;92(6):669-73. doi: 10.1038/clpt.2012.179.
Molecular medicine is moving beyond genomics to encompass the new scientific field of epigenetics. First described as a conceptual model of how genes might interact with their surroundings to produce a phenotype, epigenomic research currently investigates mechanisms of nongenetic modification contributing to gene regulation and examines the impact of these changes on human health and behavior.
分子医学正在超越基因组学,涵盖新的表观遗传学科学领域。表观遗传学最初被描述为一种概念模型,即基因如何与周围环境相互作用产生表型,目前的表观基因组学研究调查了非遗传修饰对基因调控的贡献机制,并研究了这些变化对人类健康和行为的影响。