Lonsdale B, Tarry D W, Bowen F L, Stansfield D G
Ciba-Geigy Agrochemicals, Whittlesford, Cambridge.
Vet Rec. 1990 Mar 3;126(9):207-10.
The results of trials on eight farms to assess the efficacy of two pour-on formulations containing cyromazine for the prevention of cutaneous myiasis of sheep are presented; data from trials on sheep with larval implants and on sheep kept in cages with adult flies are also reported. The incidence of cutaneous myiasis was reduced by between 87 per cent and 100 per cent for eight weeks when a formulation containing 6 per cent w/v cyromazine was used at an application rate of 60 to 85 mg of active ingredient/kg bodyweight. When a formulation containing 10 per cent w/v was used at an application rate of 50 to 100 mg/kg, the incidence of the condition was reduced by between 90 per cent and 100 per cent for eight weeks. Studies of sheep with larval implants, using the formulation containing 10 per cent w/v cyromazine at 50, 100 and 150 mg/kg bodyweight gave variable results with some animals at each dose rate having lost protection by the seventh week. When sheep were treated with the formulation containing 10 per cent w/v cyromazine at 50 or 100 mg/kg and exposed to adult flies in fly-proof cages they were completely protected for nine and eight weeks, respectively.
本文介绍了在八个农场进行的试验结果，以评估两种含环丙氨嗪的浇泼剂对预防绵羊皮肤蝇蛆病的效果；还报告了对植入幼虫的绵羊和饲养在装有成年苍蝇笼子里的绵羊进行试验的数据。当使用含6%（w/v）环丙氨嗪的制剂，按60至85毫克活性成分/千克体重的施用量给药时，皮肤蝇蛆病的发病率在八周内降低了87%至100%。当使用含10%（w/v）环丙氨嗪的制剂，按50至100毫克/千克的施用量给药时，该病的发病率在八周内降低了90%至100%。对植入幼虫的绵羊进行的研究表明，使用含10%（w/v）环丙氨嗪的制剂，按50、100和150毫克/千克体重给药，结果各不相同，每个剂量率的一些动物在第七周时失去了保护作用。当绵羊用含10%（w/v）环丙氨嗪的制剂，按50或100毫克/千克体重进行处理，并置于防蝇笼中接触成年苍蝇时，它们分别在九周和八周内得到了完全保护。
