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猫视网膜中Y神经节细胞的非线性通路。

The nonlinear pathway of Y ganglion cells in the cat retina.

作者信息

Victor J D, Shapley R M

出版信息

J Gen Physiol. 1979 Dec;74(6):671-89. doi: 10.1085/jgp.74.6.671.

DOI:10.1085/jgp.74.6.671
PMID:231636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2228574/
Abstract

Retinal ganglion cells of the Y type in the cat retina produce two different types of response: linear and nonlinear. The nonlinear responses are generated by a separate and independent nonlinear pathway. The functional connectivity in this pathway is analyzed here by comparing the observed second-order frequency responses of Y cells with predictions of a "sandwich model" in which a static nonlinear stage is sandwiched between two linear filters. The model agrees well with the qualitative and quantitative features of the second-order responses. The prefilter in the model may well be the bipolar cells and the nonlinearity and postfilter in the model are probably associated with amacrine cells.

摘要

猫视网膜中Y型视网膜神经节细胞产生两种不同类型的反应:线性反应和非线性反应。非线性反应由一条独立的非线性通路产生。通过将观察到的Y细胞二阶频率反应与“三明治模型”的预测结果进行比较,分析了该通路中的功能连接性。在“三明治模型”中,一个静态非线性阶段夹在两个线性滤波器之间。该模型与二阶反应的定性和定量特征吻合良好。模型中的前置滤波器很可能是双极细胞,模型中的非线性和后置滤波器可能与无长突细胞有关。