Wienbar Sophia, Schwartz Gregory W
Departments of Ophthalmology and Physiology, Feinberg School of Medicine, Northwestern University, United States.
Prog Retin Eye Res. 2018 Nov;67:102-117. doi: 10.1016/j.preteyeres.2018.06.003. Epub 2018 Jun 23.
Retinal ganglion cells (RGCs) were one of the first classes of sensory neurons to be described in terms of a receptive field (RF). Over the last six decades, our understanding of the diversity of RGC types and the nuances of their response properties has grown exponentially. We will review the current understanding of RGC RFs mostly from studies in mammals, but including work from other vertebrates as well. We will argue for a new paradigm that embraces the fluidity of RGC RFs with an eye toward the neuroethology of vision. Specifically, we will focus on (1) different methods for measuring RGC RFs, (2) RF models, (3) feature selectivity and the distinction between fluid and stable RF properties, and (4) ideas about the future of understanding RGC RFs.
视网膜神经节细胞（RGCs）是最早根据感受野（RF）进行描述的一类感觉神经元。在过去的六十年里，我们对RGC类型的多样性及其反应特性的细微差别有了指数级的增长。我们将主要从哺乳动物的研究中回顾目前对RGC感受野的理解，但也包括其他脊椎动物的研究成果。我们将提出一种新的范式，该范式接受RGC感受野的流动性，着眼于视觉神经行为学。具体来说，我们将关注（1）测量RGC感受野的不同方法，（2）感受野模型，（3）特征选择性以及流动和稳定感受野特性之间的区别，以及（4）关于理解RGC感受野未来的想法。
