假地衣酸 Pseudocyphellaria coriifolia（地衣）中的二萜和三萜及其对克氏锥虫 Trypanosoma cruzi 的生物活性。
Depsides and triterpenes in Pseudocyphellaria coriifolia (lichens) and biological activity against Trypanosoma cruzi.
机构信息
Facultad de Farmacia, Universidad de Valparaíso, Av. Gran Bretaña N 1093, Valparaíso, Chile.
出版信息
Nat Prod Res. 2013;27(17):1607-10. doi: 10.1080/14786419.2012.740033. Epub 2012 Nov 19.
The lichen Pseudocyphellaria coriifolia is a species endemic to southern South America. From the lichen thallus, methyl evernate, tenuiorin and three hopane triterpenoids were isolated and identified as the main lichen constituents. Their trypanocidal effects were screened against epimastigotes of Trypanosoma cruzi. The results of the biological test showed that some hopane terpenoids exhibit antiparasitic properties.
地衣 Pseudocyphellaria coriifolia 是一种仅分布于南美洲南部的特有物种。从地衣体中分离并鉴定出甲基 evernate、tenuiorin 和三种藿烷三萜类化合物作为主要的地衣成分。对这些化合物进行了抗 Trypanosoma cruzi 前鞭毛体的生物活性筛选，结果表明部分藿烷三萜类化合物具有抗寄生虫活性。
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