Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
Magn Reson Imaging. 2013 May;31(4):624-9. doi: 10.1016/j.mri.2012.09.008. Epub 2012 Nov 17.
The purpose was to describe the design and fabrication of a driver suitable for magnetic resonance elastography (MRE) of the head and neck and to assess its performance in evaluating human parotid gland, lymph nodes and thyroid at 3.0 T.
A head and neck driver was fabricated using a commercial transducer, headrest mould and piston extension. Driver performance was tested using a motion-sensitized spin-echo MRE pulse sequence. Six healthy volunteers and three patients (two metastatic nodes and one papillary carcinoma) were evaluated using MRE. Viscoelastic maps were computed to obtain storage modulus (G') and loss modulus (G") of the normal parotid and thyroid, metastatic node and thyroid cancer. Reproducibility was assessed by coefficient of variation.
All subjects completed MRE examination without discomfort. Initial G' and G" values were as follows: normal parotid gland, 1.12 kPa and 0.48 kPa; thyroid, 0.58 kPa and 0.42 kPa; metastatic node, 0.66 kPa and 0.58 kPa; and thyroid cancer, 0.17 kPa and 0.28 kPa. Based on parotid data, the coefficient of variation for G' and G" was 4.7% and 9.8%.
A new MRE driver for head and neck was successfully implemented, and our initial results suggested the device was suitable for the mechanical assessment of tissues in the head and neck.
本研究旨在描述一种适用于头颈部磁共振弹性成像（MRE）的驱动器的设计和制造，并评估其在 3.0T 下评估人腮腺、淋巴结和甲状腺的性能。
使用商业换能器、头枕模具和活塞延伸件制造头颈部驱动器。使用运动敏感的自旋回波 MRE 脉冲序列测试驱动器性能。对六名健康志愿者和三名患者（两个转移性淋巴结和一个甲状腺乳头状癌）进行 MRE 评估。通过计算粘弹性图来获得正常腮腺和甲状腺、转移性淋巴结和甲状腺癌的存储模量（G'）和损耗模量（G"）。通过变异系数评估重复性。
所有受试者均顺利完成 MRE 检查，无不适。初始 G'和 G"值如下：正常腮腺，1.12kPa 和 0.48kPa；甲状腺，0.58kPa 和 0.42kPa；转移性淋巴结，0.66kPa 和 0.58kPa；甲状腺癌，0.17kPa 和 0.28kPa。根据腮腺数据，G'和 G"的变异系数分别为 4.7%和 9.8%。
成功实现了一种新的头颈部 MRE 驱动器，我们的初步结果表明该设备适用于头颈部组织的机械评估。
