Pepin Kay M, Ehman Richard L, McGee Kiaran P
Mayo Graduate School, United States.
Department of Radiology, United States.
Prog Nucl Magn Reson Spectrosc. 2015 Nov;90-91:32-48. doi: 10.1016/j.pnmrs.2015.06.001. Epub 2015 Jun 23.
Tissue mechanical properties are significantly altered with the development of cancer. Magnetic resonance elastography (MRE) is a noninvasive technique capable of quantifying tissue mechanical properties in vivo. This review describes the basic principles of MRE and introduces some of the many promising MRE methods that have been developed for the detection and characterization of cancer, evaluation of response to therapy, and investigation of the underlying mechanical mechanisms associated with malignancy.
随着癌症的发展,组织的力学特性会发生显著改变。磁共振弹性成像(MRE)是一种能够在体内定量组织力学特性的非侵入性技术。本综述描述了MRE的基本原理,并介绍了为癌症的检测和特征描述、治疗反应评估以及与恶性肿瘤相关的潜在力学机制研究而开发的众多有前景的MRE方法中的一些。