Zhang Zhiyuan, Zhang Jian, Luo Wugen, Jiang Hongqun
Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Aug;26(15):692-3, 696.
To explore the effect of surgery added with antifungal agents in treatment of fungal rhinosinusitis.
One hundred and two consecutive patients with fungal rhinosinusitis were randomly divided into two groups: the control group (n=48) were treated with surgery alone, the treatment group (n=54) were treated with surgery plus antifungal therapy during operation and postoperation. The patients were followed up for 6 months and the relapse rates between two groups were compared.
No relapse was observed in the treatment group. The relapse rate of the control group was 20.8% (P < 0.01).
Surgery plus antifungal therapy can prevent the relapse of fungal rhinosinusitis significantly.
探讨手术联合抗真菌药物治疗真菌性鼻窦炎的效果。
将102例连续性真菌性鼻窦炎患者随机分为两组：对照组（n = 48）仅接受手术治疗，治疗组（n = 54）在手术中和术后接受手术联合抗真菌治疗。对患者进行6个月的随访，并比较两组之间的复发率。
治疗组未观察到复发。对照组的复发率为20.8%（P < 0.01）。
手术联合抗真菌治疗可显著预防真菌性鼻窦炎的复发。
