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是否应该提倡男性包皮环切术以预防生殖器癌症?

Should male circumcision be advocated for genital cancer prevention?

作者信息

Morris Brian J, Mindel Adrian, Tobian Aaron Ar, Hankins Catherine A, Gray Ronald H, Bailey Robert C, Bosch Xavier, Wodak Alex D

机构信息

Molecular Medical Sciences, University of Sydney, Australia.

出版信息

Asian Pac J Cancer Prev. 2012;13(9):4839-42. doi: 10.7314/apjcp.2012.13.9.4839.

DOI:10.7314/apjcp.2012.13.9.4839
PMID:23167429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3668781/
Abstract

The recent policy statement by the Cancer Council of Australia on infant circumcision and cancer prevention and the announcement that the quadrivalent human papillomavirus (HPV) vaccine will be made available for boys in Australia prompted us to provide an assessment of genital cancer prevention. While HPV vaccination of boys should help reduce anal cancer in homosexual men and cervical cancer in women, it will have little or no impact on penile or prostate cancer. Male circumcision can reduce cervical, penile and possibly prostate cancer. Promotion of both HPV vaccination and male circumcision will synergistically maximize genital cancer prevention.

摘要

澳大利亚癌症理事会最近发布的关于婴儿包皮环切术与癌症预防的政策声明,以及宣布将在澳大利亚为男孩提供四价人乳头瘤病毒(HPV)疫苗,促使我们对生殖器癌症预防进行评估。虽然男孩接种HPV疫苗应有助于减少男同性恋者的肛门癌和女性的宫颈癌,但对阴茎癌或前列腺癌几乎没有影响。男性包皮环切术可降低宫颈癌、阴茎癌,可能还包括前列腺癌的发病风险。推广HPV疫苗接种和男性包皮环切术将协同作用,最大限度地预防生殖器癌症。

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本文引用的文献

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Male circumcision reduces penile high-risk human papillomavirus viral load in a randomised clinical trial in Rakai, Uganda.在乌干达拉凯的一项随机临床试验中,男性割礼可降低阴茎高危型人乳头瘤病毒载量。
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Circumcision and the risk of prostate cancer.割礼与前列腺癌风险。
Cancer. 2012 Sep 15;118(18):4437-43. doi: 10.1002/cncr.26653. Epub 2012 Mar 12.
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