真菌在鼻和鼻窦疾病中的作用。
The role of fungi in diseases of the nose and sinuses.
机构信息
Division of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
出版信息
Am J Rhinol Allergy. 2012 Sep-Oct;26(5):351-8. doi: 10.2500/ajra.2012.26.3807.
BACKGROUND
Human exposure to fungal elements is inevitable, with normal respiration routinely depositing fungal hyphae within the nose and paranasal sinuses. Fungal species can cause sinonasal disease, with clinical outcomes ranging from mild symptoms to intracranial invasion and death. There has been much debate regarding the precise role fungal species play in sinonasal disease and optimal treatment strategies.
METHODS
A literature review of fungal diseases of the nose and sinuses was conducted.
RESULTS
Presentation, diagnosis, and current management strategies of each recognized form of fungal rhinosinusitis was reviewed.
CONCLUSION
Each form of fungal rhinosinusitis has a characteristic presentation and clinical course, with the immune status of the host playing a critical pathophysiological role. Accurate diagnosis and targeted treatment strategies are necessary to achieve optimal outcomes.
背景
人类不可避免地会接触到真菌，正常呼吸通常会使真菌菌丝沉积在鼻腔和鼻旁窦内。真菌物种可引起鼻-鼻窦疾病，临床结果从轻微症状到颅内侵犯和死亡不等。关于真菌物种在鼻-鼻窦疾病中的确切作用以及最佳治疗策略存在很多争论。
方法
对鼻腔和鼻窦的真菌病文献进行了回顾。
结果
综述了每种已识别的真菌性鼻-鼻窦炎的表现、诊断和当前的治疗策略。
结论
每种形式的真菌性鼻-鼻窦炎都有其特征性的表现和临床过程，宿主的免疫状态起着关键的病理生理作用。为了获得最佳结果，需要准确的诊断和有针对性的治疗策略。
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