Zainea Viorel, Ionita Irina Gabriela, Pituru Silviu, Pietroșanu Cătălina, Rusescu Andreea, Stefanescu Cristian Dragos, Gherghiceanu Florentina, Anghelina Florin, Palade Dragos, Hainarosie Razvan
Department of ENT, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of ENT, 'Prof. Dr. D. Hociota' Institute of Phonoaudiology and Functional ENT Surgery, 061344 Bucharest, Romania.
Exp Ther Med. 2022 Jan;23(1):77. doi: 10.3892/etm.2021.11000. Epub 2021 Nov 25.
Sinonasal mucormycosis is an extremely challenging pathology for the ear, nose and throat (ENT) surgeon from a therapeutic point of view. The disease affects immunocompromised patients and exhibits lethal potential. Although the diagnosis is relatively easy to suspect due to the distinctive clinical aspects which consists of black crusting present in the nasal fossae able to be confirmed by biopsy, the treatment requires resection of all affected tissue with safety limits. Due to the tendency of invasion associated with this fungal infection and taking into account the location involved (the sinonasal area) and the grave condition of these patients, it is extremely important to perform only the minimal resection necessary, but that includes all tissue infected by the fungus. This article presents a minimally invasive method of evaluation that can be performed during endoscopic surgical intervention and that aids the surgeon to better evaluate the affected area. It is associated with no additional risks for the patients, but it helps the surgeon to perform the intervention efficiently while not damaging healthy tissue. The authors consider that the method presented will aid the surgeon during the endoscopic surgical intervention in evaluating the lesion and resecting all the affected tissue while preserving healthy areas.
从治疗角度来看,鼻窦毛霉菌病对于耳鼻喉科(ENT)外科医生而言是一种极具挑战性的病症。该疾病影响免疫功能低下的患者,并具有致命的可能性。尽管由于其独特的临床症状(包括鼻腔内可见黑色结痂,可通过活检确诊)相对容易怀疑诊断,但治疗需要切除所有受影响的组织并达到安全边界。鉴于这种真菌感染具有侵袭性,考虑到受累部位(鼻窦区域)以及这些患者的严重病情,仅进行必要的最小限度切除非常重要,但这包括所有被真菌感染的组织。本文介绍了一种可在内镜手术干预期间进行的微创评估方法,该方法有助于外科医生更好地评估受影响区域。它不会给患者带来额外风险,但有助于外科医生高效地进行干预,同时不损伤健康组织。作者认为所介绍的方法将有助于外科医生在内镜手术干预期间评估病变并切除所有受影响的组织,同时保留健康区域。