Cirone Mara, Di Renzo Livia, Lotti Lavinia V, Conte Valeria, Trivedi Pankaj, Santarelli Roberta, Gonnella Roberta, Frati Luigi, Faggioni Alberto
Department of Experimental Medicine; Istituto Pasteur-Fondazione Cenci Bolognetti; Sapienza University; Rome, Italy.
Oncoimmunology. 2012 Oct 1;1(7):1218-1219. doi: 10.4161/onci.20428.
A growing number of studies indicate that cell death can be either immunogenic or not, depending on its modalities, the type and the activation state of the cells, and finally, the environment where it happens. Increased understanding of the immunogenicity of cancer cell death will significantly improve the outcome of chemotherapeutic treatments.
越来越多的研究表明，细胞死亡可能具有免疫原性，也可能没有，这取决于其方式、细胞类型和激活状态，以及最终细胞死亡发生的环境。对癌细胞死亡免疫原性的深入了解将显著改善化疗治疗的效果。
