Thomson A H, Beardsmore C S, Firmin R, Leanage R, Simpson H
Department of Child Health, University of Leicester.
Arch Dis Child. 1990 Feb;65(2):171-4. doi: 10.1136/adc.65.2.171.
Aortic arch anomalies in infancy often cause intrathoracic airway obstruction. Airway function was assessed as part of the diagnostic evaluation in six symptomatic infants both by plethysmography and using a chest compression technique to obtain partial flow-volume loops. Two infants had normal intrathoracic airway function and their symptoms were unrelated to aortic arch abnormalities. The remaining four had complete vascular rings (three double aortic arch, one pulmonary sling) and had increased expiratory airway resistance (Raw) (mean Raw = 700% predicted) and greatly decreased maximum flow rates at functional residual capacity (VmaxFRC; mean VmaxFRC = 34% predicted) with gross shape abnormalities of the flow-volume loop. Postoperatively airway function was substantially improved (mean Raw = 175% predicted, VmaxFRC = 79% predicted) but some abnormality of flow-volume loop shape remained, suggesting that tracheal dynamics were not completely normal in the early postoperative period.
婴儿期主动脉弓异常常导致胸内气道梗阻。作为诊断评估的一部分,采用体积描记法并使用胸部按压技术获取部分流量-容积环,对6例有症状婴儿的气道功能进行了评估。2例婴儿胸内气道功能正常,其症状与主动脉弓异常无关。其余4例有完整的血管环(3例双主动脉弓,1例肺动脉吊带),呼气气道阻力(Raw)增加(平均Raw =预测值的700%),功能残气量时的最大流速(VmaxFRC)大幅降低(平均VmaxFRC =预测值的34%),流量-容积环有明显形态异常。术后气道功能有显著改善(平均Raw =预测值的175%,VmaxFRC =预测值的79%),但流量-容积环形态仍有一些异常,提示术后早期气管动力学尚未完全恢复正常。