Godfrey S, Bar-Yishay E, Arad I, Landau L I, Taussig L M
Pediatrics. 1983 Oct;72(4):517-22.
Partial expiratory flow-volume maneuvers have been performed on nine occasions on six infants with a variety of pulmonary problems using a new technique for thoracic compression. The infants were placed within an inflatable bag that was, itself, within a canvas bag. By sudden controlled inflation of the inner bag at end inspiration, partial expiratory flow-volume curves were generated and recorded by means of a face mask and pneumotachograph. By comparing these flow results with those airway resistance and lung volume measurements obtained from the infants in whole body plethysmography and by noting the effect of inhaling a helium/oxygen gas mixture, it was possible to partition the airway obstruction between large and small airways. The presence of small airway obstruction was noted in the absence of changes in airway resistance or lung volume in several instances. A complete evaluation of airway function should include this test of forced expiration for greater understanding and treatment of lung disease in infancy.
采用一种新的胸部按压技术，对6名患有各种肺部问题的婴儿进行了9次部分呼气流量-容积操作。将婴儿置于一个充气囊内，而该充气囊本身又置于一个帆布袋内。在吸气末通过突然控制充气囊的充气，借助面罩和呼吸流速计生成并记录部分呼气流量-容积曲线。通过将这些流量结果与从婴儿全身体积描记法中获得的气道阻力和肺容积测量结果进行比较，并注意吸入氦/氧混合气体的效果，就能够区分大小气道的气道阻塞情况。在一些情况下，尽管气道阻力和肺容积没有变化，但仍发现存在小气道阻塞。对气道功能进行全面评估应包括这项强制呼气测试，以便更好地理解和治疗婴儿期的肺部疾病。
