Organ Transplant Center, National Center for Child Health and Development, Setagaya-Ku, Tokyo, Japan.
Liver Transpl. 2013 Feb;19(2):226-8. doi: 10.1002/lt.23572.
Liver transplantation is now an established treatment for children with end-stage liver disease. Left lateral segment (LLS) grafts are most commonly used in split and living donor liver transplantation in children. In very small children, LLS grafts can be too large, and further nonanatomical reduction has recently been introduced to mitigate the problem of large-for-size grafts. However, the implantation of LLS grafts can be a problem in infants and very small children because of the thickness of the grafts, and these techniques do not address problems related to thickness. We herein describe a technique for reducing the thickness of living donor left lateral grafts and successful transplantation in a 2.8-kg infant with acute liver failure.
肝移植现在是治疗儿童终末期肝病的一种成熟治疗方法。左外叶(LLS)移植物是儿童劈离式和活体供肝移植中最常用的移植物。在非常小的儿童中,LLS 移植物可能过大,最近引入了进一步的非解剖性缩小技术来减轻大体积移植物的问题。然而,由于移植物的厚度,LLS 移植物的植入在婴儿和非常小的儿童中可能成为一个问题,并且这些技术不能解决与厚度相关的问题。我们在此描述了一种用于减少活体供体左外叶移植物厚度的技术,并成功地将其移植到一名患有急性肝衰竭的 2.8 公斤婴儿中。