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身体变化:抗逆转录病毒疗法与艾滋病毒/艾滋病感染者的脂肪代谢障碍综合征

Body changes: antiretroviral therapy and lipodystrophy syndrome in people living with HIV/AIDS.

作者信息

Tsuda Luciana Castelar, da Silva Mariana Machado, Machado Alcyone Artioli, Fernandes Ana Paula Morais

机构信息

Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.

出版信息

Rev Lat Am Enfermagem. 2012 Sep-Oct;20(5):847-53. doi: 10.1590/s0104-11692012000500005.

DOI:10.1590/s0104-11692012000500005
PMID:23174828
Abstract

OBJECTIVE

to identify the different types of morphological alterations from lipodystrophy syndrome (LS) in outpatients and relate them to the therapeutic regimen used.

METHOD

a cross-sectional study which recruited 60 patients with HIV and LS and 79 without LS, who consented to interview and data collection from their medical notes.

RESULTS

the region most affected by lipoatrophy was the face; by lipohypertrophy, the abdomen, and by the mixed form, the alterations to the abdomen, face, and upper and lower limbs.

CONCLUSION

among the therapeutic regimens, that comprised of zidovudine, lamivudine and efavirenz seemed to protect against LS. Nursing can act in the early identification of the changes, as well as providing guidance and support for patients affected by the changes in their body image.

摘要

目的

识别门诊患者脂肪代谢障碍综合征(LS)的不同类型形态学改变,并将其与所采用的治疗方案相关联。

方法

一项横断面研究,招募了60例患有HIV和LS的患者以及79例无LS的患者,这些患者同意接受访谈并从其病历中收集数据。

结果

最受脂肪萎缩影响的部位是面部;脂肪增生影响的是腹部,而混合型则影响腹部、面部以及上肢和下肢。

结论

在治疗方案中,由齐多夫定、拉米夫定和依非韦伦组成的方案似乎可预防LS。护理工作可在早期识别这些变化,同时为受身体形象变化影响的患者提供指导和支持。

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