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Anticoagulant-induced priapism progressing to penile gangrene: a devastating complication!抗凝剂诱发的阴茎异常勃起进展为阴茎坏疽：一种毁灭性的并发症！
BMJ Case Rep. 2012 Nov 21;2012:bcr2012007073. doi: 10.1136/bcr-2012-007073.
2
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[Priapism treated by caverno-glandular shunt, caverno-saphenous shunt and caverno-spongiosum shunt: report of a case].[阴茎海绵体-尿道海绵体分流术、阴茎海绵体-大隐静脉分流术及阴茎海绵体-尿道海绵体分流术治疗阴茎异常勃起：1例报告]
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本文引用的文献

1
Penile gangrene: an unusual complication of priapism in a patient with bladder carcinoma.阴茎坏疽：一名膀胱癌患者阴茎异常勃起的罕见并发症。
J Surg Tech Case Rep. 2011 Jan;3(1):37-9. doi: 10.4103/2006-8808.78470.
2
Penile gangrene: a devastating and lethal entity.阴茎坏疽：一种毁灭性的致命病症。
Saudi J Kidney Dis Transpl. 2011 Mar;22(2):359-61.
3
Warfarin-induced penile necrosis in a patient with heparin-induced thrombocytopenia.华法林诱导伴肝素诱导血小板减少症患者阴茎坏死。
J Korean Med Sci. 2010 Sep;25(9):1390-3. doi: 10.3346/jkms.2010.25.9.1390. Epub 2010 Aug 16.
4
Priapism and penile gangrene due to thrombotic thrombocytopenic purpura.因血栓性血小板减少性紫癜导致的阴茎异常勃起和阴茎坏疽。
Urology. 2010 Jan;75(1):71-2. doi: 10.1016/j.urology.2009.04.036. Epub 2009 Nov 6.
5
Dry gangrene of the penis induced by a bullring for sexual stimulation purposes.因用于性刺激目的的阴茎环导致的阴茎干性坏疽。
ScientificWorldJournal. 2008 Sep 21;8:896-900. doi: 10.1100/tsw.2008.128.
6
Penile gangrene due to severe vascular calcification.严重血管钙化导致的阴茎坏疽。
Isr Med Assoc J. 2006 Dec;8(12):888-9.
7
Warfarin-induced skin necrosis.华法林所致皮肤坏死。
Br J Haematol. 2004 Sep;126(5):628. doi: 10.1111/j.1365-2141.2004.05095.x.
8
Low molecular weight heparin induced priapism.低分子量肝素诱发阴茎异常勃起。
J Urol. 2004 Jul;172(1):263. doi: 10.1097/01.ju.0000132155.38285.8e.
9
HEPARIN AND THROMBUS FORMATION: EARLY SUPPRESSION AND LATE ENHANCEMENT.肝素与血栓形成：早期抑制与晚期增强
Br J Haematol. 1963 Oct;9:548-51. doi: 10.1111/j.1365-2141.1963.tb05479.x.
10
Heparin-induced priapism.肝素诱导的阴茎异常勃起。
Int J Impot Res. 2001 Dec;13(6):357-9. doi: 10.1038/sj.ijir.3900759.

抗凝剂诱发的阴茎异常勃起进展为阴茎坏疽：一种毁灭性的并发症！

Anticoagulant-induced priapism progressing to penile gangrene: a devastating complication!

作者信息

Nagathan Deepak Sharanappa, Pahwa Harvinder Singh, Kumar Awanish, Goel Apul

机构信息

Department of Urology, Chhatrapati Shahuji Maharaj Medical University, Erstwhile King George Medical College, Lucknow, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2012 Nov 21;2012:bcr2012007073. doi: 10.1136/bcr-2012-007073.

DOI:10.1136/bcr-2012-007073
PMID:23175010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4543925/
Abstract

A 35-year-old man developed priapism with the use of low-molecular-weight heparin and warfarin following repair of left brachial artery sustained after gunshot injury. Priapism progressed to penile gangrene despite decompression and distal shunt procedure leading to total penectomy and perineal urethrostomy. We describe the mechanism of anticoagulant (heparin and warfarin)-induced penile gangrene and the possible methods to avert such a devastating complication.

摘要

一名35岁男性在枪伤后左肱动脉修复术后使用低分子量肝素和华法林时发生了阴茎异常勃起。尽管进行了减压和远端分流手术，但阴茎异常勃起仍发展为阴茎坏疽，最终导致全阴茎切除术和会阴尿道造口术。我们描述了抗凝剂（肝素和华法林）诱导阴茎坏疽的机制以及避免这种毁灭性并发症的可能方法。