Nagathan Deepak Sharanappa, Pahwa Harvinder Singh, Kumar Awanish, Goel Apul
Department of Urology, Chhatrapati Shahuji Maharaj Medical University, Erstwhile King George Medical College, Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2012 Nov 21;2012:bcr2012007073. doi: 10.1136/bcr-2012-007073.
A 35-year-old man developed priapism with the use of low-molecular-weight heparin and warfarin following repair of left brachial artery sustained after gunshot injury. Priapism progressed to penile gangrene despite decompression and distal shunt procedure leading to total penectomy and perineal urethrostomy. We describe the mechanism of anticoagulant (heparin and warfarin)-induced penile gangrene and the possible methods to avert such a devastating complication.
一名35岁男性在枪伤后左肱动脉修复术后使用低分子量肝素和华法林时发生了阴茎异常勃起。尽管进行了减压和远端分流手术,但阴茎异常勃起仍发展为阴茎坏疽,最终导致全阴茎切除术和会阴尿道造口术。我们描述了抗凝剂(肝素和华法林)诱导阴茎坏疽的机制以及避免这种毁灭性并发症的可能方法。