Nazififard Mohammad, Mahdizadeh Simin, Suh Kune Y
Department of Nuclear Engineering, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.
Radiat Prot Dosimetry. 2013 May;154(4):510-6. doi: 10.1093/rpd/ncs266. Epub 2012 Nov 21.
A real-time automatic dose dispenser (RADD) has been designed and fabricated for automatic withdrawal and calibration of diagnostic radiopharmaceuticals such as those labelled with (99m)Tc. This system enhances the accuracy and precision of activity measurements and reduces personal radiation exposure. The structure, function, user-friendliness and performance of this device are described and examined for diagnostic activities of (99m)Tc ranging from 50 to 650 MBq. The results show that the RADD minimises the likelihood of miscalibration of radiopharmaceuticals due to human error and results in significantly reduced variability (i.e. higher precision) in dispensed activities of radiopharmaceuticals.
已设计并制造了一种实时自动剂量分配器（RADD），用于自动抽取和校准诊断用放射性药物，例如那些用（99m）Tc标记的药物。该系统提高了活度测量的准确性和精密度，并减少了个人辐射暴露。描述并检验了该设备在50至650 MBq的（99m）Tc诊断活度下的结构、功能、用户友好性和性能。结果表明，RADD将因人为误差导致放射性药物校准错误的可能性降至最低，并显著降低了放射性药物分配活度的变异性（即更高的精密度）。
