Medical Physics Unit, Santa Maria della Misericordia Hospital, Rovigo, Italy.
J Radiol Prot. 2020 Mar;40(1):243-252. doi: 10.1088/1361-6498/ab4287. Epub 2019 Sep 9.
Recently new mobile systems for dispensing positron emitters have been produced, designed to guarantee dispensing cycles in an aseptic environment. The aim of the present work was to assess the advantage of one of these systems in radiation protection of operators in clinical settings.
Recently, in our centre the new self-dispensing system named KARL by Tema Sinergie was adopted for F-FDG radiopharmaceuticals. The system is associated with an automatic Rad-inject infuser. The system that was previously used was a fixed isolator NMC DSI (Tema Sinergie), equipped with a μDDS-An activity fractioning system, together with a pneumatic post for the syringe delivery. The dosimetric evaluations on both systems were carried out through environmental measurements with an ionisation chamber and with the use of personal dosimeters.
The operations of preparation and administration of F-FDG dose to the patient, with the use of Karl + RadInject, involve exposures much lower than those obtained by the fixed isolator. The average body exposure of the technician was reduced by 31%, and for the physician by 77%. On the extremities, the equivalent dose to the hands of the technician was reduced by 78%, and for the physician by 96%. Also the additional dosimeters worn by the technician confirmed the estimated environmental assessments.
The exposures of the working personnel were significantly reduced with the introduction of the new KARL system.
最近，新的正电子发射体分配移动系统已经问世，旨在保证在无菌环境下进行分配循环。本研究旨在评估其中一种系统在临床环境下对操作人员辐射防护方面的优势。
最近，我们中心采用了名为 KARL 的新型自配药系统，用于 F-FDG 放射性药物。该系统与自动 Rad-inject 注射器相连。之前使用的系统是一个带有 μDDS-An 活性分离系统的固定隔离器 NMC DSI（Tema Sinergie），以及一个用于注射器输送的气动后位。通过电离室进行环境测量和使用个人剂量计对两种系统进行了剂量评估。
使用 Karl + RadInject 进行 F-FDG 剂量的准备和施药操作，暴露量远低于固定隔离器。技术员的平均身体暴露量减少了 31%，医生的暴露量减少了 77%。在四肢部位，技术员手部的等效剂量减少了 78%，医生的等效剂量减少了 96%。此外，技术员佩戴的额外剂量计也证实了预估的环境评估结果。
引入新的 KARL 系统后，工作人员的暴露量显著降低。
