食管原发性恶性黑色素瘤，广泛累及上皮内。
Primary malignant melanoma of the esophagus with extensive intraepithelial extension.
机构信息
Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, and Department of Surgical Pathology, Kumamoto University Hospital, Kumamoto, Japan.
出版信息
Ann Thorac Surg. 2012 Dec;94(6):2105-7. doi: 10.1016/j.athoracsur.2012.04.127.
Primary malignant melanoma of the esophagus (PMME) is an exceedingly rare tumor. The prognosis of PMME is very poor, and the 5-year survival rate is only 2.2% due to its aggressive biologic character. We present patient with PMME with wide extension into almost the entire esophagus, without endoscopic abnormalities. This patient's presentation is extremely valuable because it has enabled us to observe the long-term natural progression of PMME, including recurrent disease with a wide range of atypical melanocytic cells in the entire esophagus.
食管原发性恶性黑色素瘤（PMME）是一种极为罕见的肿瘤。由于其侵袭性的生物学特性，PMME 的预后非常差，5 年生存率仅为 2.2%。我们报告了一例 PMME 广泛侵犯食管几乎全部的病例，内镜检查未见异常。该患者的表现极具价值，因为它使我们能够观察到 PMME 的长期自然进展，包括复发性疾病和整个食管内广泛存在的非典型黑色素细胞。
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