Friedrich T, Emmrich P
Chirurgische Klinik I, Universität Leipzig.
Zentralbl Chir. 1998;123(3):276-9.
Primary malignant melanoma of the esophagus is extremely rare. Less than 200 cases have been published worldwide up to now. We report a case of a 65-years old male suffering from dysphagia for four months. The endoscopy showed a polypoidal tumor of black colour in the distal part of the esophagus. The histological diagnosis of the initial biopsy specimen was melanoma. Partial esophagectomy and lymph node sampling were performed. The resected specimen showed a polypoid tumor with black pigmentation of 8 x 5 x 3 centimeter. Histopathology revealed a primary malignant melanoma of the esophagus stage pT2 pN1 M0 and grading three. The patient died 8 months after resection from general metastatic disease. Age, sex, symptoms, duration of symptoms and time of survival are similar as described in former cases.
原发性食管恶性黑色素瘤极为罕见。截至目前,全球已发表的病例不足200例。我们报告一例65岁男性,吞咽困难4个月。内镜检查显示食管远端有一个黑色的息肉样肿瘤。最初活检标本的组织学诊断为黑色素瘤。进行了部分食管切除术和淋巴结取样。切除标本显示一个8×5×3厘米的有黑色色素沉着的息肉样肿瘤。组织病理学显示为食管原发性恶性黑色素瘤,分期为pT2 pN1 M0,分级为三级。患者在切除术后8个月因全身转移疾病死亡。年龄、性别、症状、症状持续时间和生存时间与以前病例所描述的相似。