Ballerini L, Mullins C E, Cifarelli A, Pasquini L, De Simone G, Giannico S, Guccione P, Di Donato R, Di Carlo D
Ospedale Bambino Gesú, Roma, Italy.
Cathet Cardiovasc Diagn. 1990 Mar;19(3):165-9. doi: 10.1002/ccd.1810190304.
Eight-six children (aged 20 days to 14 years, 20 under age 1 year) underwent 94 percutaneous balloon valvuloplasty for pulmonary valve stenosis. The patients were divided into three groups: typical pulmonary valve stenosis (71), pulmonary valve dysplasia (9), and residual stenosis after surgical valvotomy for pulmonary atresia with intact ventricular septum (PAIS) (6). Each of the three groups was divided into two subgroups. In the early cases, balloon catheters with diameter 10-20% exceeding pulmonary valve annulus were used and the drop of the gradient was 39.5%. In the later cases, balloon diameters 30-40% greater than the valve anulus or double balloons were used and a drop of 66.7% in the RV-PA pressure gradient was achieved. The dilation in patients with dysplastic valve and residual stenosis after surgical valvotomy for PAIS was less effective. Doppler echocardiography was the technique used to evaluate residual gradient. Six months to 4 years follow-up demonstrated a persistent decrease of the valve gradient.
86名儿童(年龄从20天至14岁,其中20名年龄在1岁以下)接受了94次经皮肺动脉瓣球囊成形术治疗肺动脉瓣狭窄。患者被分为三组:典型肺动脉瓣狭窄(71例)、肺动脉瓣发育不良(9例)以及室间隔完整的肺动脉闭锁(PAIS)手术瓣膜切开术后残余狭窄(6例)。这三组又各自分为两个亚组。在早期病例中,使用直径比肺动脉瓣环大10%-20%的球囊导管,压力阶差下降了39.5%。在后期病例中,使用直径比瓣膜环大30%-40%的球囊或双球囊,右心室-肺动脉压力阶差下降了66.7%。对于发育不良瓣膜患者以及PAIS手术瓣膜切开术后残余狭窄患者,扩张效果较差。采用多普勒超声心动图技术评估残余压力阶差。6个月至4年的随访显示瓣膜压力阶差持续下降。